ALEXANDER (Jerome), cardinal and archbishop of Brindisi, was born in 1480; and distinguished himself at the beginning of the reformation, by the opposition he made to Luther: for being sent into Germany as the pope's nuncio in 1519, he acted, as occasion served, in the character both of ambassador and doctor; and declaimed three hours together against Luther's doctrine before the diet of Worms, but could not prevent that celebrated reformer from being heard in that diet. He published several works, and died at Rome in 1542.