ANTONIO, the most noted architect of the family of SANGALLO, was a nephew, on his mother's side, to the two preceding, but whose father was Bartolomeo Picconi, a cooper of Mugello. He was born in 1487, but what precise year in the decade cannot now be ascertained. Originally a carpenter, he was subsequently led to visit Rome, whither he had been drawn by the fame of his uncles. As those noted architects left the capital shortly after his arrival, he had the good fortune to find a protector in Bramante, then a man well advanced in years. He soon drew upon himself the notice of Cardinal Farnese, afterwards Paul III., for whom he built a splendid mansion in the Campo de' Fiori, which would have been sufficient to have established his reputation. He subsequently erected numerous private palazzi, and among others his own house in the Strada Giulia, now the Palazzo Sacchetti. He was employed on military architecture for a number of years at Civitavecchia, Parma, Piacenza, Ancona, &c.; when he was, on the death of Peruzzi, chosen sole architect for the completion of St Peter's. He modelled a design of this splendid edifice, nearly 20 English feet in length, which, although broken into a multiplicity of parts, are yet agreeably proportioned, and the tout ensemble is decidedly picturesque; but the fabric of Sangallo was entirely abandoned after his death. (See Wood's Letters of an Architect.) Sangallo's greatest work is undoubtedly the Palazzo Farnese; but he must share the fame of the design with Michel Angelo, who drew the magnificent and majestic cornice which distinguishes this building from every other of the kind in Rome. The style and manner of this ancient building has been reproduced in the Reform Club-house, Pall Mall, London. Antonio Sangallo died at Terni, in the month of October 1546, leaving behind him a wide reputation of having been, according to Vasari, "a most excellent architect." (Vasari's Lives of Painters, Sculptors, and Architects, by Mrs Foster, vol. iv., 1851.)