(Sir Anthony), descended from Sir Thomas Cooke lord mayor of London, was born in 1506, and supposed to have been educated at Cambridge. He was so eminent for his learning, piety, and prudence, that the guardians of king Edward VI appointed him to be his chief instructor in learning, and to form his manners. He had four daughters; and being resolved to have sons by education, lest he should have none none by birth, he taught his daughters those lessons by night that he had instilled into the prince by day: he was happy in his endeavours, as they proved learned in Greek and Latin, and equally distinguished by virtue, piety, and good fortune. Mildred was married to the great lord Burleigh; Ann to Sir Nicholas Bacon, lord keeper of the great seal; Elizabeth to Sir John Ruffell, son and heir of Francis earl of Bedford; and Catharine to Sir Henry Killigrew. He lived in exile during the Marian persecution; and returning on the accession of queen Elizabeth, spent the rest of his days in peace and honour, dying in 1576.