(anc. geog.) a district of Macedonia, to the north of the Sinus Thermaicus, and east of the river Axios, which separates it from Bottiaë, and west of the river Strymon, (Pliny). Also a district of Mæopotamia, which took its name from that of Macedonìa, running along the Euphrates, from Zeugma down to Thapsacus; extending a great way east, because Nitibis was reckoned to it.