(Dr John), descended from a good family in Huntingdonshire, was born in 1631. He was educated in Trinity-college, Cambridge, and qualified himself for the profession of physic; and in 1675 was chosen professor of that art at Gresham college. He translated Dr Sydenham's Observationes Medicae circa morborum acutorum historiam et curationem into the Latin, and Sydenham dedicated them to Mapletoft. He married in 1679, and soon after transferred his studies from physic to divinity; took orders; obtained the vicarage of St Laurence Jewry, with the lectureship of St Christopher's in London; and having been a benefactor to Sion college, was, in 1707, elected president. He continued to preach in his church of St Laurence Jewry till he was above 80 years of age; and in his decline printed a book intitled The principles and duties of the Christian religion, &c. 8vo. 1710, a copy of which he sent to every house in his parish. He was a polite scholar; and besides some other pieces on moral and theological subjects, there are in the Appendix to Ward's Lives of the professors of Gresham-college, three Latin lectures read there by him, on the origin of the art of medicine, and the history of its invention.