(Humphry) was born at Padstow in Cornwall in 1648, and was honourably defended by both parents. Three years he studied at Westminster under Dr Bury; and then was removed to Christchurch, Oxford. Here he published, in 1676, his Marmora Oxoniensia ex Arundelianis, Seldenianis, aliique confitata, cum perpetuo Commentario. This introduced him to the lord chancellor Finch, afterward earl of Nottingham, who in 1679 presented him to the rectory of St Clements near Oxford, and in 1681 bestowed on him a prebend of Norwich. Some years after he was engaged in a controversy with the Papists at Norwich, concerning the validity of the orders of the church of England, which produced his book upon that subject. In 1688 he was installed in the archdeaconry of Suffolk; to which he was collated by Dr Lloyd, then bishop of Norwich. In 1691, upon the death of Dr Edward Pococke, the Hebrew professorship at Oxford being vacant, was offered to Dr Prideaux, but he refused it. In 1697, he published his Life of Mahomet, and in 1702 was installed dean of Norwich. In 1710 he was cut for the stone, which interrupted his studies for more than a year. Some time after his return to London, he proceeded with his Connection of the History of the Old and New Testament; which he had begun when he laid aside the design of writing the History of Appropriations. He died in 1724.