Manipule, amongst the Romans, was a small body of infantry, which in the time of Romulus consisted of one hundred men, and in the time of the consuls, and first Caesars, of two hundred. See the article Army.

Manipulus is also an ecclesiastical ornament, worn by the priests, deacons, and subdeacons in the Roman Catholic church.

Manipulus, amongst physicians, is used to signify a handful of herbs or leaves, or as much as a man can grasp in his hand at once; a quantity which is frequently denoted by the abbreviation M. or m.