eans numerous. The most important of them is his Treatise on Artificial Anus, in which the principles laid down by John Hunter are happily applied. In his operations he was remarkable for the skill and dexterity with which he overcame the numerous difficulties incidental to so extensive a practice as he enjoyed. Instead of attempting to introduce new methods of procedure, he commonly limited himself to modifying and adapting to his particular exigencies the established laws of surgery. In private life, Dupuytren was cold and reserved; his brow, furrowed with wrinkles, betrayed the weight of cares with which he was burdened; and it was seldom that a smile, except one of irony or disdain, played about his lips. His unsocial coldness was further heightened by his constant struggle against a consumptive tendency, which ultimately carried him off, 8th February 1835.

After death Dupuytren's head was opened, and his brain taken out and weighed. Its weight was found to be exactly the same with that of Dr Abercrombie, viz. 64 ounces.